Percona Mysql my.cnf review

MySQL & MariaDB Other MySQL® Questions
1

Can you please review my config file for any suggestions.

	Quad core Xeon
	8GB of ram
	
	Main drive is 512 raid 1
	
	Mysql drive is ssd
	
	[mysqldump]
	quick
	[mysql]
	no-auto-rehash
	[myisamchk]
	key_buffer=256M
	key_buffer_size=32M
	write_buffer=2M
	read_buffer=2M
	sort_buffer_size=256M
	[client]
	socket="/mysql/mysql.sock"
	[mysqld]
	# INNODB #
	innodb_flush_method = O_DIRECT
	innodb_log_files_in_group = 2
	#innodb_log_file_size = 256M
	innodb_flush_log_at_trx_commit = 1
	innodb_file_per_table = 1
	innodb_buffer_pool_size = 4G
	
	wait_timeout = 600 seconds
	
	# CACHES AND LIMITS #
	tmp_table_size = 32M
	max_heap_table_size = 32M
	query_cache_type = 0
	query_cache_size = 32M
	max_connections = 100
	thread_cache_size = 50
	open_files_limit = 65535
	table_definition_cache = 4096
	table_open_cache = 10240
	
	# LOGGING #
	log_error = /mysql/mysql-error.log
	log_queries_not_using_indexes = 1
	slow_query_log = 1
	slow_query_log_file = /mysql/mysql-slow.log
	
	loose_handlersocket_port = 9998
	# the port number to bind to for read requests
	loose_handlersocket_port_wr = 9999
	# the port number to bind to for write requests
	loose_handlersocket_threads = 16
	# the number of worker threads for read requests
	loose_handlersocket_threads_wr = 1
	# the number of worker threads for write requests
	# to allow handlersocket to accept many concurrent
	# connections, make open_files_limit as large as
	# possible.
	
	#join_buffer_size=12M
	#thread_concurrency=4
	#query_cache_limit=256M
	#connect_timeout=1000
	#key_buffer=384M
	#table_cache=4096
	#max_user_connections=50
	#local-infile=0
	#server-id=14
	#wait_timeout=1000
	#read_rnd_buffer_size=16M
	#read_buffer_size=2M
	#myisam_sort_buffer_size=64M
	#max_allowed_packet=32M
	#socket="/mysql/mysql.sock"
	#skip-external-locking
	#sort_buffer_size=2M
	#datadir="/mysql"
	#[mysqlhotcopy]
	#interactive-timeout
2

Why this is commented out:
#innodb_log_file_size = 256M

If you use InnoDB tables, then using default size if far from being optimal. If you are on 5.5.x+ then you should use large innodb logs, like 512M+

Also innodb_buffer_pool_size = 4G so 50% of you current total memory - whether it is OK depends on if the machine is MySQL dedicated and if you use MyISAM and how much data is distributed among InnoDB and MyISAM tables.