Yeah with only 2GB of swap listed, I’d be surprised if this was causing an issue, especially on SSD (somewhat moot point, but a point none the less). You have your buffer pool set to about 62.5% of your total memory, which may be too high considering you are running multiple services on the same DB server that will be competing for memory. Have you done any checks to see what your buffer pool situation looks like, such as how much is actually being used (show global status – > Innodb_buffer_pool_pages_free and Innodb_buffer_pool_pages_total), what your churn is (show engine innodb status → evicted without access)? Point being with some analysis you might be able to lower the buffer pool without any performance hit depending on your DB load.