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MySQL performance good after restart, than it drops
We are running a MySQL community server version 5.7.27-1 on a debian system. Every time we restart the MySQL server our data load is done in 3.5 hours, the second run is most of the time at the same speed, than the performance drops and it takes up to 8 hours to process the same data until we restart the MySQL server.
What could cause such a significant performance degradation?